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Emerging roles of telomeric chromatin alterations in cancer

Abstract Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the specific complex named shelterin and a...

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Autors principals: Stefano Cacchione, Annamaria Biroccio, Angela Rizzo
Format: Artigo
Idioma:Inglês
Publicat: BMC 2019-01-01
Col·lecció:Journal of Experimental & Clinical Cancer Research
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Accés en línia:http://link.springer.com/article/10.1186/s13046-019-1030-5
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