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Emerging roles of telomeric chromatin alterations in cancer

Abstract Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the specific complex named shelterin and a...

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Bibliografische gegevens
Hoofdauteurs: Stefano Cacchione, Annamaria Biroccio, Angela Rizzo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2019-01-01
Reeks:Journal of Experimental & Clinical Cancer Research
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Online toegang:http://link.springer.com/article/10.1186/s13046-019-1030-5
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