A novel role of Krüppel-like factor 8 as an apoptosis repressor in hepatocellular carcinoma

Abstract Background Krüppel-like factor 8 (KLF8), a cancer-promoting factor that regulates critical gene transcription and cellular cancer-related events, has been implicated in tumor development and progression. However, the functional role of KLF8 in the pathogenesis of hepatocellular carcinoma (H...

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Detalhes bibliográficos
Main Authors: Ming-Da Wang, Hao Xing, Chao Li, Lei Liang, Han Wu, Xin-Fei Xu, Li-Yang Sun, Meng-Chao Wu, Feng Shen, Tian Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-08-01
Colecção:Cancer Cell International
Assuntos:
Hepatocellular carcinoma
KLF8
Apoptosis
H3K27 acetylation
HMGA2
MMP7
Acesso em linha:http://link.springer.com/article/10.1186/s12935-020-01513-3
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