Iron oxide nanoparticles induce reversible endothelial-to-mesenchymal transition in vascular endothelial cells at acutely non-cytotoxic concentrations

Abstract Background Iron oxide nanoparticles (IONPs) have been extensively studied in different biomedical fields. Recently, the non-cytotoxic concentration of IONPs induced cell-specific response raised concern of their safety. Endothelial cell exposure was unavoidable in their applications, while...

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Main Authors: Tao Wen, Lifan Du, Bo Chen, Doudou Yan, Aiyun Yang, Jian Liu, Ning Gu, Jie Meng, Haiyan Xu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-07-01
Series:Particle and Fibre Toxicology
Assuntos:
Iron oxide nanoparticle
Endothelial-to-mesenchymal transition
Reactive oxygen species
Reversible
Acceso en liña:http://link.springer.com/article/10.1186/s12989-019-0314-4
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