Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies

Abstract Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based therapy of immune-mediated, inflammatory, and degenerative diseases, due to their immunosuppressive, immunomodulatory, and regenerative potentials. Preclinical studies and clinical trials have demonstrated...

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Hlavní autoři: Nádia de Cássia Noronha, Amanda Mizukami, Carolina Caliári-Oliveira, Juçara Gastaldi Cominal, José Lucas M. Rocha, Dimas Tadeu Covas, Kamilla Swiech, Kelen C. R. Malmegrim
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-05-01
Edice:Stem Cell Research & Therapy
Témata:
Mesenchymal stromal cells
Priming
Cell therapy
Pro-inflammatory cytokines
Pharmaceutical drugs
Biomaterials
On-line přístup:http://link.springer.com/article/10.1186/s13287-019-1224-y
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