Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer

The epidermis is the outermost layer of the skin and provides a protective barrier against environmental insults. It is a rapidly-renewing tissue undergoing constant regeneration, maintained by several types of stem cells. The Hedgehog (HH) signaling pathway is one of the fundamental signaling pathw...

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Bibliographic Details
Main Authors: Yoshinori Abe, Nobuyuki Tanaka
Format: Artigo
Language:Inglês
Published: MDPI AG 2017-11-01
Series:Journal of Developmental Biology
Subjects:
Hedgehog signaling
epidermis
hair follicle
development
homeostasis
basal cell carcinoma
signaling crosstalk
Online Access:https://www.mdpi.com/2221-3759/5/4/12
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