Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E

Abstract Background Extracellular matrix proteins tenascin-C (TNC) and periostin, which were identified as T-helper cell type 2 cytokine-induced genes in human bronchial epithelial cells, accumulate in the airway basement membrane of asthmatic patients. Although serum periostin has been accepted as...

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Main Authors: Mina Yasuda, Norihiro Harada, Sonoko Harada, Ayako Ishimori, Yoko Katsura, Yukinari Itoigawa, Kei Matsuno, Fumihiko Makino, Jun Ito, Junya Ono, Kazunori Tobino, Hisaya Akiba, Ryo Atsuta, Kenji Izuhara, Kazuhisa Takahashi
Format: Artigo
Jezik:Inglês
Izdano: BMC 2018-11-01
Serija:Allergy, Asthma & Clinical Immunology
Teme:
Tenascin-C
Periostin
Asthma
Type 2 biomarker
Immunoglobulin E
Online dostop:http://link.springer.com/article/10.1186/s13223-018-0300-7
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