Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E

Abstract Background Several lines of evidence suggest that high-density lipoprotein (HDL) reduces Alzheimer’s disease (AD) risk by decreasing vascular beta-amyloid (Aβ) deposition and inflammation, however, the mechanisms by which HDL improve cerebrovascular functions relevant to AD remain poorly un...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jerome Robert, Emily B. Button, Emma M. Martin, Luke McAlary, Zoe Gidden, Megan Gilmour, Guilaine Boyce, Tara M. Caffrey, Andrew Agbay, Amanda Clark, Judith M. Silverman, Neil R. Cashman, Cheryl L. Wellington
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2020-03-01
Cyfres:Molecular Neurodegeneration
Pynciau:
Alzheimer’s disease
Cerebrovasculature
High-density lipoprotein (HDL)
Cerebral amyloid angiopathy (CAA)
Endothelial inflammation
Apolipoprotein (apo)E
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s13024-020-00366-8
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