Inhibitory Effect of Selaginellins from Selaginella tamariscina (Beauv.) Spring against Cytochrome P450 and Uridine 5′-Diphosphoglucuronosyltransferase Isoforms on Human Liver Microsomes

Selaginella tamariscina (Beauv.) has been used for traditional herbal medicine for treatment of cancer, hepatitis, and diabetes in the Orient. Numerous bioactive compounds including alkaloids, flavonoids, lignans, and selaginellins have been identified in this medicinal plant. Among them, selaginell...

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Hlavní autoři: Jae-Kyung Heo, Phi-Hung Nguyen, Won Cheol Kim, Nguyen Minh Phuc, Kwang-Hyeon Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2017-09-01
Edice:Molecules
Témata:
cytochrome P450
drug interaction
mass spectrometry
selaginellins
uridine 5′-diphosphoglucuronosyltransferase
On-line přístup:https://www.mdpi.com/1420-3049/22/10/1590
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