Inhibitory Effect of Selaginellins from Selaginella tamariscina (Beauv.) Spring against Cytochrome P450 and Uridine 5′-Diphosphoglucuronosyltransferase Isoforms on Human Liver Microsomes

Selaginella tamariscina (Beauv.) has been used for traditional herbal medicine for treatment of cancer, hepatitis, and diabetes in the Orient. Numerous bioactive compounds including alkaloids, flavonoids, lignans, and selaginellins have been identified in this medicinal plant. Among them, selaginell...

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Main Authors: Jae-Kyung Heo, Phi-Hung Nguyen, Won Cheol Kim, Nguyen Minh Phuc, Kwang-Hyeon Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-09-01
Colecção:Molecules
Assuntos:
cytochrome P450
drug interaction
mass spectrometry
selaginellins
uridine 5′-diphosphoglucuronosyltransferase
Acesso em linha:https://www.mdpi.com/1420-3049/22/10/1590
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