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Insights into the N-sulfation mechanism: molecular dynamics simulations of the N-sulfotransferase domain of NDST1 and mutants.
Sulfation patterns along glycosaminoglycan (GAG) chains dictate their functional role. The N-deacetylase N-sulfotransferase family (NDST) catalyzes the initial downstream modification of heparan sulfate and heparin chains by removing acetyl groups from subsets of N-acetylglucosamine units and, subse...
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Main Authors: | , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science (PLoS)
2013-01-01
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Sraith: | PLoS ONE |
Rochtain Ar Líne: | http://europepmc.org/articles/PMC3733922?pdf=render |
Clibeanna: |
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