Insights into the N-sulfation mechanism: molecular dynamics simulations of the N-sulfotransferase domain of NDST1 and mutants.

Sulfation patterns along glycosaminoglycan (GAG) chains dictate their functional role. The N-deacetylase N-sulfotransferase family (NDST) catalyzes the initial downstream modification of heparan sulfate and heparin chains by removing acetyl groups from subsets of N-acetylglucosamine units and, subse...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tarsis F Gesteira, Laércio Pol-Fachin, Vivien Jane Coulson-Thomas, Marcelo A Lima, Hugo Verli, Helena B Nader
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3733922?pdf=render
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares