CCND1 as a predictive biomarker of neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma.

BACKGROUND: Cyclin D1 (CCND1) has been associated with chemotherapy resistance and poor prognosis. In this study, we tested the hypothesis that CCND1 expression determines response and clinical outcomes in locally advanced head and neck squamous cell carcinoma (HNSCC) patients treated with neoadjuva...

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Main Authors: Zhien Feng, Wei Guo, Chenping Zhang, Qin Xu, Ping Zhang, Jian Sun, Hanguang Zhu, Zhonghe Wang, Jiang Li, Lizhen Wang, Bingshun Wang, Guoxin Ren, Tong Ji, Wenyong Tu, Xihu Yang, Weiliu Qiu, Li Mao, Zhiyuan Zhang, Wantao Chen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3204964?pdf=render
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