Subinhibitory Concentration of Colistin Promotes the Conjugation Frequencies of Mcr-1- and blaNDM-5-Positive Plasmids

ABSTRACT Horizontal gene transfer (HGT) plays a significant role in the spread of antibiotic resistance genes (ARGs). Most reported compounds promote HGT by increasing the cell membrane permeability. Colistin has been reported to increase the cell membrane permeability when exhibiting its antibacter...

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Detalhes bibliográficos
Main Authors: Xia Xiao, Fuxin Zeng, Ruichao Li, Yuan Liu, Zhiqiang Wang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-04-01
Colecção:Microbiology Spectrum
Assuntos:
colistin
conjugation frequency
plasmid
horizontal gene transfer
ARGs
Acesso em linha:https://journals.asm.org/doi/10.1128/spectrum.02160-21
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