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Deletion of glyceraldehyde‐3‐phosphate dehydrogenase (gapN) in Clostridium saccharoperbutylacetonicum N1‐4(HMT) using CLEAVE™ increases the ATP pool and accelerates solvent production
Summary The development and advent of mutagenesis tools for solventogenic clostridial species in recent years has allowed for the increased refinement of industrially relevant strains. In this study we have utilised CLEAVE™, a CRISPR/Cas genome editing system developed by Green Biologics Ltd., to en...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2022-05-01
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| Colecção: | Microbial Biotechnology |
| Acesso em linha: | https://doi.org/10.1111/1751-7915.13990 |
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