Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani.

The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....

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Autores principales: Jessica L Martin, Phillip A Yates, Radika Soysa, Joshua F Alfaro, Feng Yang, Kristin E Burnum-Johnson, Vladislav A Petyuk, Karl K Weitz, David G Camp, Richard D Smith, Phillip A Wilmarth, Larry L David, Gowthaman Ramasamy, Peter J Myler, Nicola S Carter
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2014-02-01
Colección:PLoS Pathogens
Acceso en línea:http://europepmc.org/articles/PMC3937319?pdf=render
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