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Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.
Myostatin (Mstn) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Mstn(-/-) mice have a dramatic increase in muscle mass, reduction in fat mass, and resistance to diet-induced and genetic obesity. To determine how Mstn deleti...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2009-01-01
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| Sarja: | PLoS ONE |
| Linkit: | http://europepmc.org/articles/PMC2654157?pdf=render |
| Tagit: |
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