TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.

Regulation of apical calcium entry is important for the function of principal cells of the collecting duct. However, the molecular identity and the regulators of the transporter/channel, which is responsible for apical calcium entry and what factors regulate the calcium conduction remain unclear.We...

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Main Authors: Zhi-Ren Zhang, Wen-Feng Chu, Binlin Song, Monika Gooz, Jia-Ning Zhang, Chang-Jiang Yu, Shuai Jiang, Aleksander Baldys, Pal Gooz, Stacy Steele, Grzegorz Owsianik, Bernd Nilius, Peter Komlosi, P Darwin Bell
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3745395?pdf=render
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