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Deletion of Atbf1/Zfhx3 In Mouse Prostate Causes Neoplastic Lesions, Likely by Attenuation of Membrane and Secretory Proteins and Multiple Signaling Pathways

The ATBF1/ZFHX3 gene at 16q22 is the second most frequently mutated gene in human prostate cancer and has reduced expression or mislocalization in several types of human tumors. Nonetheless, the hypothesis that ATBF1 has a tumor suppressor function in prostate cancer has not been tested. In this stu...

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Main Authors: Xiaodong Sun, Xiaoying Fu, Jie Li, Changsheng Xing, Henry F. Frierson, Hao Wu, Xiaokun Ding, Tongzhong Ju, Richard D. Cummings, Jin-Tang Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-05-01
Colecção:Neoplasia: An International Journal for Oncology Research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1476558614000542
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