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Discovery of bioactive nitrated lipids and nitro-lipid-protein adducts using mass spectrometry-based approaches

Nitro-fatty acids (NO2-FA) undergo reversible Michael adduction reactions with cysteine and histidine residues leading to the post-translational modification (PTM) of proteins. This electrophilic character of NO2-FA is strictly related to their biological roles. The NO2-FA-induced PTM of signaling p...

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Autors principals: Tânia Melo, Javier-Fernando Montero-Bullón, Pedro Domingues, M. Rosário Domingues
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019-05-01
Col·lecció:Redox Biology
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2213231718310243
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