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Formalin fixation at low temperature provides better yield and integrity of DNA

Introduction: Fixation with formalin, a widely used procedure to preserve tissue samples, leads to damage of DNA through crosslinking activity. The factors that could influence the fixation and integrity of DNA may be numerous: incubation time, tissue type, concentration of formalin, temperature, pH...

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Detalhes bibliográficos
Main Authors: Makulović Stefan, Vitošević Katarina, Slović Živana, Todorović Miloš, Todorović Danijela
Formato: Artigo
Idioma:Inglês
Publicado em: University of Belgrade, Medical Faculty 2019-01-01
Colecção:Medicinski Podmladak
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Acesso em linha:https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2019/0369-15271902037M.pdf
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