Association Between DPP-4 Inhibitors and Events of Colorectal and Liver Cancers in Patients With Diabetes Receiving Second-Line Agents: A Nested Case-Control Study

ObjectivePlasma dipeptidyl peptidase-4 (DPP4) levels were significantly lower in patients with colorectal and liver cancers, and animal studies also showed DPP4 inhibitors (DPP4is) have procarcinogenic effects in colorectal cancer. Until now, whether DPP4is therapy affects the progression of liver c...

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Main Authors: Chu-Lin Chou, Shu-Hui Juan, Ching-Hao Li, Hsi-Hsien Chen, Chih-Chin Kao, Li-Ying Chen, Li-Nien Chien, Te-Chao Fang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Assuntos:
DPP-4 inhibitors
colorectal cancer
liver cancer
second-line agents
type 2 diabetes mellitus
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2022.840142/full
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