Inconsistent protective efficacy and marked polymorphism limits the value of Schistosoma japonicum tetraspanin-2 as a vaccine target.

BACKGROUND: Schistosoma mansoni tetraspanin 2 (Sm-TSP-2) has been shown to be strongly recognized by IgG1 and IgG3 antibodies from individuals putatively resistant to schistosome infection, but not chronically infected people, and to induce high levels of protection against challenge infection in th...

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Detaylı Bibliyografya
Asıl Yazarlar: Wenbao Zhang, Jun Li, Mary Duke, Malcolm K Jones, Ling Kuang, Jianfeng Zhang, David Blair, Yuesheng Li, Donald P McManus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2011-01-01
Seri Bilgileri:PLoS Neglected Tropical Diseases
Online Erişim:http://europepmc.org/articles/PMC3104969?pdf=render
Etiketler: Etiketle
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