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Prodrug Strategies for Paclitaxel

Paclitaxel is an anti-tumor agent with remarkable anti-tumor activity and wide clinical uses. However, it is also faced with various challenges especially for its poor water solubility and low selectivity for the target. To overcome these disadvantages of paclitaxel, approaches using small molecule...

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Main Authors: Ziyuan Meng, Quanxia Lv, Jun Lu, Houzong Yao, Xiaoqing Lv, Feng Jiang, Aiping Lu, Ge Zhang
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2016-05-01
Series:International Journal of Molecular Sciences
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Acceso en liña:http://www.mdpi.com/1422-0067/17/5/796
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