Virus/Host Cell Crosstalk in Hypoxic HPV-Positive Cancer Cells

Oncogenic types of human papillomaviruses (HPVs) are major human carcinogens. The expression of the viral E6/E7 oncogenes plays a key role for HPV-linked oncogenesis. It recently has been found that low oxygen concentrations (“hypoxia”), as present in sub-regions of HPV-positive cancers, strongly af...

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Detalhes bibliográficos
Main Authors: Karin Hoppe-Seyler, Julia Mändl, Svenja Adrian, Bianca J. Kuhn, Felix Hoppe-Seyler
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-07-01
Colecção:Viruses
Assuntos:
human papillomavirus
hypoxia
cervical cancer
head and neck cancer
senescence
metabolism
mTOR
therapy
Acesso em linha:https://www.mdpi.com/1999-4915/9/7/174
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