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Identification of Novel Covalent XPO1 Inhibitors Based on a Hybrid Virtual Screening Strategy
Nuclear export protein 1 (XPO1), a member of the nuclear export protein-p (Karyopherin-P) superfamily, regulates the transport of “cargo” proteins. To facilitate this important process, which is essential for cellular homeostasis, XPO1 must first recognize and bind the cargo proteins. To inhibit thi...
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Main Authors: | , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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MDPI AG
2022-04-01
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叢編: | Molecules |
主題: | |
在線閱讀: | https://www.mdpi.com/1420-3049/27/8/2543 |
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