microRNA-206 modulates an Rtn4a/Cxcr4a/Thbs3a axis in newly forming somites to maintain and stabilize the somite boundary formation of zebrafish embryos

Although microRNA-206 (miR-206) is known to regulate proliferation and differentiation of muscle fibroblasts, the role of miR-206 in early-stage somite development is still unknown. During somitogenesis of zebrafish embryos, reticulon4a (rtn4a) is specifically repressed by miR-206. The somite bounda...

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Main Authors: Cheng-Yung Lin, Jun-Yu He, Chih-Wei Zeng, Moo-Rumg Loo, Wen-Yen Chang, Po-Hsiang Zhang, Huai-Jen Tsai
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017-01-01
Colecção:Open Biology
Assuntos:
zebrafish
somite boundary formation
mir-206
rtn4a
cxcr4a
thbs3a
Acesso em linha:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170009
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