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Approaches to detect genetic effects that differ between two strata in genome-wide meta-analyses: Recommendations based on a systematic evaluation.

Genome-wide association meta-analyses (GWAMAs) conducted separately by two strata have identified differences in genetic effects between strata, such as sex-differences for body fat distribution. However, there are several approaches to identify such differences and an uncertainty which approach to...

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Detalhes bibliográficos
Main Authors: Thomas W Winkler, Anne E Justice, L Adrienne Cupples, Florian Kronenberg, Zoltán Kutalik, Iris M Heid, GIANT consortium
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5531538?pdf=render
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