Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD

Abstract Background The mechanisms underlying airflow obstruction in COPD cannot be distinguished by standard spirometry. We ascertain whether mathematical modeling of airway biomechanical properties, as assessed from spirometry, could provide estimates of emphysema presence and severity, as quantif...

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Detalhes bibliográficos
Main Authors: Mariaelena Occhipinti, Matteo Paoletti, Brian J. Bartholmai, Srinivasan Rajagopalan, Ronald A. Karwoski, Cosimo Nardi, Riccardo Inchingolo, Anna R. Larici, Gianna Camiciottoli, Federico Lavorini, Stefano Colagrande, Vito Brusasco, Massimo Pistolesi
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-05-01
Colecção:Respiratory Research
Assuntos:
Pulmonary emphysema
COPD
Small airway disease
Respiratory function tests
Spirometry
Tomography
Acesso em linha:http://link.springer.com/article/10.1186/s12931-019-1049-3
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