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Recombination Enhances HIV-1 Envelope Diversity by Facilitating the Survival of Latent Genomic Fragments in the Plasma Virus Population.

HIV-1 is subject to immune pressure exerted by the host, giving variants that escape the immune response an advantage. Virus released from activated latent cells competes against variants that have continually evolved and adapted to host immune pressure. Nevertheless, there is increasing evidence th...

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Detalhes bibliográficos
Main Authors: Taina T Immonen, Jessica M Conway, Ethan O Romero-Severson, Alan S Perelson, Thomas Leitner
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-12-01
Colecção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC4687844?pdf=render
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