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The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts.
BACKGROUND:Glutathione is considered essential for survival in mammalian cells and yeast but not in prokaryotic cells. The presence of a nuclear pool of glutathione has been demonstrated but its role in cellular proliferation and differentiation is still a matter of debate. PRINCIPAL FINDINGS:We hav...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2009-07-01
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| Schriftenreihe: | PLoS ONE |
| Online Zugang: | http://europepmc.org/articles/PMC2712766?pdf=render |
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