The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts.

BACKGROUND:Glutathione is considered essential for survival in mammalian cells and yeast but not in prokaryotic cells. The presence of a nuclear pool of glutathione has been demonstrated but its role in cellular proliferation and differentiation is still a matter of debate. PRINCIPAL FINDINGS:We hav...

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Hlavní autoři: Jelena Markovic, Nancy J Mora, Ana M Broseta, Amparo Gimeno, Noelia de-la-Concepción, José Viña, Federico V Pallardó
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2009-07-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC2712766?pdf=render
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