Receptor-G Protein Interaction Studied by Bioluminescence Resonance Energy Transfer: Lessons From Protease-Activated Receptor 1

Since its development, the bioluminescence resonance energy transfer (BRET) approach has been extensively applied to study G protein-coupled receptors (GPCRs) in real time and in live cells. One of the major aspects of GPCRs investigated in considerable details is their physical coupling to the hete...

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Auteurs principaux: Mohammed Akli eAYOUB, Abdulrahman eAl-Senaidy, Jean-Philippe ePin
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2012-06-01
Collection:Frontiers in Endocrinology
Sujets:
BRET
G proteins
precoupling
protein interactions
PAR1
Preassembly
Accès en ligne:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00082/full
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