Co-encapsulation of thymoquinone with docetaxel enhances the encapsulation efficiency into PEGylated liposomes and the chemosensitivity of MCF7 breast cancer cells to docetaxel

Combinatorial therapeutic strategies to eradicate tumors can be superior to a single therapeutic modality. Docetaxel (DT) has been approved for the treatment of local or metastasized breast cancer alone or in combination with other chemotherapeutic agents. Thymoquinone (TQ) originated from the seeds...

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Hauptverfasser: Fadwa Odeh, Randa Naffa, Hanan Azzam, Ismail S. Mahmoud, Walhan Alshaer, Abeer Al Bawab, Said Ismail
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019-11-01
Schriftenreihe:Heliyon
Schlagworte:
Cancer research
Pharmaceutical science
Breast cancer
Docetaxel
Thymoquinone
Liposomes
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2405844019365788
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