Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers

Abstract Background/aim Evidence shows that Luminal A breast cancer is likely to undergo bone metastasis, but the mechanisms involved remain unknown. This study’s aim was to demonstrate a correlation between estrogen receptor (ER) positivity and bone metastasis as the clinically preferred site of me...

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Autori principali: Jen-Hwey Chiu, Che-Sheng Wen, Jir-You Wang, Chih-Yi Hsu, Yi-Fang Tsai, Shih-Chieh Hung, Ling-Ming Tseng, Yi-Ming Shyr
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2017-05-01
Serie:Journal of Translational Medicine
Soggetti:
Estrogen receptor
Breast cancer
Snail
Bone metastasis
p190 RhoGAP
Accesso online:http://link.springer.com/article/10.1186/s12967-017-1192-x
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