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Retinoid-X receptor agonists increase thyroid hormone competence in lower jaw remodeling of pre-metamorphic Xenopus laevis tadpoles

Thyroid hormone (TH) signaling plays critical roles during vertebrate development, including regulation of skeletal and cartilage growth. TH acts through its receptors (TRs), nuclear hormone receptors (NRs) that heterodimerize with Retinoid-X receptors (RXRs), to regulate gene expression. A defining...

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Detalhes bibliográficos
Main Authors: Brenda J. Mengeling, Lara F. Vetter, J. David Furlow
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2022-01-01
Colecção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007347/?tool=EBI
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