Enhanced osteoarthritis therapy by nanoengineered mesenchymal stem cells using biomimetic CuS nanoparticles loaded with plasmid DNA encoding TGF-β1

Mesenchymal stem cells (MSCs) therapy shows the potential benefits to relieve clinical symptoms of osteoarthritis (OA), but it is uncertain if it can repair articular cartilage lesions — the main pathology of OA. Here, we prepared biomimetic cupper sulfide@phosphatidylcholine (CuS@PC) nanoparticles...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu Cai, Cuixi Wu, Qianhua Ou, Muhui Zeng, Song Xue, Jieli Chen, Yao Lu, Changhai Ding
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: KeAi Communications Co., Ltd. 2023-01-01
Cyfres:Bioactive Materials
Pynciau:
Osteoarthritis
Stem cell therapy
Cartilage regeneration
Cupper sulfide nanoparticles
Gene delivery
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2452199X22001918
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