Tanshinone IIA Promotes Pulmonary Artery Smooth Muscle Cell Apoptosis in Vitro by Inhibiting the JAK2/STAT3 Signaling Pathway

Background: Tanshinone IIA inhibits the proliferation of pulmonary artery smooth muscle cells (PASMCs), but the potential mechanisms of its effects on PASMCs apoptosis remain unclear. Methods: Rat were subjected to hypoxia for 9 days with or without Tanshinone IIA treatment. PASMCs were exposed to t...

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Autors principals: Minggang Chen, Yumei Liu, Dan Yi, Liuping Wei, Yumei Li, Li Zhang
Format: Artigo
Idioma:Inglês
Publicat: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Col·lecció:Cellular Physiology and Biochemistry
Matèries:
Tanshinone IIA
PASMCs
JAK2/STAT3
Apoptosis
Cx43
Accés en línia:http://www.karger.com/Article/FullText/358682
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