Data-Driven Model of Postsynaptic Currents Mediated by NMDA or AMPA Receptors in Striatal Neurons

The majority of excitatory synapses in the brain uses glutamate as neurotransmitter, and the synaptic transmission is primarily mediated by AMPA and NMDA receptors in postsynaptic neurons. Here, we present data-driven models of the postsynaptic currents of these receptors in excitatory synapses in m...

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Detalhes bibliográficos
Main Authors: Ilaria Carannante, Yvonne Johansson, Gilad Silberberg, Jeanette Hellgren Kotaleski
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Computational Neuroscience
Assuntos:
decay time constant
double exponential fitting
NMDA receptors
AMPA receptors
postsynaptic current
conductance-based models
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fncom.2022.806086/full
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