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Phylogenetic Gaussian process model for the inference of functionally important regions in protein tertiary structures.
A critical question in biology is the identification of functionally important amino acid sites in proteins. Because functionally important sites are under stronger purifying selection, site-specific substitution rates tend to be lower than usual at these sites. A large number of phylogenetic models...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2014-01-01
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| Colecção: | PLoS Computational Biology |
| Acesso em linha: | http://europepmc.org/articles/PMC3894161?pdf=render |
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