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eIF2α kinases regulate development through the BzpR transcription factor in Dictyostelium discoideum.

A major mechanism of translational regulation in response to a variety of stresses is mediated by phosphorylation of eIF2α to reduce delivery of initiator tRNAs to scanning ribosomes. For some mRNAs, often encoding a bZIP transcription factor, eIF2α phosphorylation leads to enhanced translation due...

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Main Authors: Charles K Singleton, Yanhua Xiong, Janet H Kirsten, Kelsey P Pendleton
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3293825?pdf=render
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