Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita

Epidermolysis bullosa acquisita (EBA) is an autoimmune skin blistering disease characterized by IgG autoantibodies (aAb) against type VII collagen (COL7). The mechanisms controlling the formation of such aAbs and their effector functions in the skin tissue are incompletely understood. Here, we asses...

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Main Authors: Balint Kovacs, Jenny Tillmann, Lisa-Christin Freund, Falk Nimmerjahn, Christian D. Sadik, Katja Bieber, Ralf J. Ludwig, Christian M. Karsten, Jörg Köhl
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-01-01
Colecção:Frontiers in Immunology
Assuntos:
Fcγ receptor
epidermolysis bullosa acquisita
autoimmunity
neutrophils
IgG
animal model
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.03012/full
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