Prmt1 upregulated by Hdc deficiency aggravates acute myocardial infarction via NETosis

Neutrophils are mobilized and recruited to the injured heart after myocardial infarction, and neutrophil count has been clinically implicated to be associated with coronary disease severity. Histidine decarboxylase (HDC) has been implicated in regulating reactive oxidative species (ROS) and the diff...

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Autori principali: Zhiwei Zhang, Suling Ding, Zhe Wang, Xiaowei Zhu, Zheliang Zhou, Weiwei Zhang, Xiangdong Yang, Junbo Ge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2022-04-01
Serie:Acta Pharmaceutica Sinica B
Soggetti:
PRMT1
HDC
Myocardial infarction
Neutrophil extracellular trap
Transcriptomics
Asymmetric demethylation arginine
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211383521004081
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