Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines

Abstract Background Chondrocytes are exposed to an inflammatory micro-environment in the extracellular matrix (ECM) of articular cartilage in joint diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA). In OA, degenerative changes and low-grade inflammation within the joint transform th...

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Main Authors: Bernadette Jeremiasse, Csaba Matta, Christopher R. Fellows, David J. Boocock, Julia R. Smith, Susan Liddell, Floris Lafeber, Willem E. van Spil, Ali Mobasheri
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-06-01
Colecção:BMC Molecular and Cell Biology
Assuntos:
Surfaceome
Aminooxy-biotin
Mass spectrometry
Proteomics
Osteoarthritis
Biomarker
Acesso em linha:http://link.springer.com/article/10.1186/s12860-020-00288-9
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