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Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases.

As one of the largest protein families, protein kinases (PKs) regulate nearly all processes within the cell and are considered important drug targets. Much research has been conducted on inhibitors for PKs, leading to a wealth of compounds that target PKs that have potential to be lead anthelmintic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Christina M Taylor, John Martin, Ramakrishna U Rao, Kerrie Powell, Sahar Abubucker, Makedonka Mitreva
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-02-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC3573124?pdf=render
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