An Epistatic Interaction between <i>Pnpla2</i> and <i>Lipe</i> Reveals New Pathways of Adipose Tissue Lipolysis

White adipose tissue (WAT) lipolysis contributes to energy balance during fasting. Lipolysis can proceed by the sequential hydrolysis of triglycerides (TGs) by adipose triglyceride lipase (ATGL), then of diacylglycerols (DGs) by hormone-sensitive lipase (HSL). We showed that the combined genetic def...

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Detalhes bibliográficos
Main Authors: Xiao Zhang, Cong Cong Zhang, Hao Yang, Krishnakant G. Soni, Shu Pei Wang, Grant A. Mitchell, Jiang Wei Wu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-04-01
Colecção:Cells
Assuntos:
transacylation
triglycerides/diacylglycerol
enzymology/enzyme mechanisms
lipolysis and fatty acid metabolism
lipids
obesity
Acesso em linha:https://www.mdpi.com/2073-4409/8/5/395
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