Combination effect of doxorubicin and HIF inhibitor on MCF-7 CD44+/CD24- subpopulation cells in hypoxic condition

Abstract Hypoxia-inducible factors (HIFs) and cancer stem cells (CSCs) are two challenging causes of radiotherapy and chemotherapy resistance, leading to most cases of failure and recurrence in breast cancer therapy. This study was conducted to investigated the inhibitory effect of combination thera...

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Bibliographic Details
Main Authors: Azadeh Rasouli, Shima Aliebrahimi, Vahideh Montazeri, Mohammad Hossein Ghahremani, Seyed Nasser Ostad
Format: Artigo
Language:Inglês
Published: Universidade de São Paulo 2022-04-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
FM19G11
Combination Index
Hypoxia-induced factor
Cytotoxicity
Cancer stem cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100555&tlng=en
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