Vaccination With Mouse Dendritic Cells Loaded With an IpaD-IpaB Fusion Provides Protection Against Shigellosis

Diarrheal diseases are a major cause of morbidity and mortality worldwide. They are most prevalent in settings with inadequate sanitation, poor hygiene and contaminated water. An important diarrheal pathogen in such settings is Shigella. No commercially available vaccine exists against shigellosis a...

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Main Authors: Olivia Arizmendi, Prashant Kumar, Qi Zheng, Jason P. Stewart, William D. Picking, Wendy Picking, Francisco J. Martinez-Becerra
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-02-01
Colecção:Frontiers in Immunology
Assuntos:
Shigella
vaccine
fusion protein
dmLT
dendritic cell
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.00192/full
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