Intracranial aneurysm’s association with genetic variants, transcription abnormality, and methylation changes in ADAMTS genes

Purpose The development of intracranial aneurysm (IA) has been linked to genetic factors. The current study examines the potential role of genes encoding disintegrin and metalloproteinase using thrombospondin motifs (ADAMTS) in IA development. Material and Methods High-throughput whole-genome and wh...

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Main Authors: Shi Chen, Mengqi Li, Wenqiang Xin, Shengze Liu, Linfei Zheng, Yan Li, Mengyao Li, Mengxiong Zhan, Xinyu Yang
Formato: Artigo
Idioma:Inglês
Publicado: PeerJ Inc. 2020-02-01
Series:PeerJ
Assuntos:
ADMTSL1
Bioinformatics
Hemorrhagic stroke
Single-nucleotide variants
Acceso en liña:https://peerj.com/articles/8596.pdf
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