The clinical effectiveness and cost-effectiveness of primary stroke prevention in children with sickle cell disease: a systematic review and economic evaluation

Background: Sickle cell disease (SCD) is a recessive genetic blood disorder, caused by a mutation in the β-globin gene. For children with SCD, the risk of stroke is estimated to be up to 250 times higher than in the general childhood population. Transcranial Doppler (TCD) ultrasonography is a non-in...

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Main Authors: MG Cherry, J Greenhalgh, L Osipenko, M Venkatachalam, A Boland, Y Dundar, K Marsh, R Dickson, DC Rees
Format: Artigo
Sprog:Inglês
Udgivet: NIHR Journals Library 2012-11-01
Serier:Health Technology Assessment
Fag:
systematic review
economic evaluation
primary stroke
children
sickle cell disease
ultrasonography
stroke
transfusion
Online adgang:https://doi.org/10.3310/hta16430
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